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Organic Acids

Organic Acids

  • Organic acids panels test for the organic acids in urine that are byproducts of daily cellular metabolism
  • Based on known metabolic pathways and enzyme-cofactor requirements, these organic acid markers can provide great insights in discovering underlying causes of chronic symptoms
  • Organic acids testing can aid advanced providers in the detection of imbalances, toxicity, and inflammation in chronically or acutely ill patients with complex illnesses
  • Alongside other diagnostic testing, organic acids profiles complete the clinical picture of root causes and guide practitioners in developing the most individual and effective interventions
  • The Vibrant Organic Acids panel uses the most advanced mass spectrometry technology to assess 75 metabolic markers in urine
  • The panel includes 11 subpanels and provides accurate evaluation of intestinal microbial overgrowth, detoxification, mitochondrial markers, neurotransmitter metabolism, glutathione status, fatty acid metabolism, and inborn errors of metabolism
  • A complete package of the Vibrant Organic Acids Panel and Vibrant Micronutrients will provide an overall picture of the patient’s whole nutrition foundation and aid the provider in intervention choices
  • Organic acids can be combined with the Vibrant Fungal Antibodies panel, the Vibrant Gut Zoomer 3.0, and the Vibrant Environmental Toxins profile to get a more specific insight into the individual’s root causes of inflammation


Not Available in New York state

Only healthcare providers licensed in their state may order laboratory testing.

  • Symptoms

    Organic acids testing can accurately identify conditions associated with genetic disorders, nutrient deficiencies, intestinal dysbiosis, and toxicity from diet and prescription drugs.

    Conditions and Symptoms Which May Benefit From Organic Acids TestingInclude:

    • Mental and/or developmental delays
    • Fatigue and weakness
    • Depression and/or anxiety
    • Dizziness
    • Mood swings
    • Difficulty concentrating
    • Nausea
    • Sleep problems
    • Slowed reaction time
    • Poor memory
    • Headache
    • Hyperactivity
    • Digestive problems
    • Abdominal pain, diarrhea, bloating
    • Hypo- or hyperglycemia
    • Unexplained weight gain/loss
    • Muscle weakness
    • Dermatitis
    • Immune deficiency
    • Anemia
    • Hearing, speech, or visual impairment
  • Markers Measured


    Yeast and Fungal Markers:

    • Citramalic Acid
    • 5-Hydroxymethyl-furoic Acid
    • 3-Oxoglutaric Acid
    • Furan-2,5-dicarboxylic Acid
    • Furancarbonylglycine
    • Tartaric Acid
    • Arabinose
    • Carboxycitric Acid
    • Tricarballylic Acid

    Bacterial Markers:

    • Hippuric Acid
    • 2-Hydroxyphenylacetic Acid
    • 4-Hydroxybenzoic Acid
    • 4-Hydroxyhippuric Acid
    • DHPPA

    Clostridia Bacterial Markers:

    • 4-Hydroxyphenylacetic Acid
    • HPHPA
    • 4-Cresol
    • 3-Indoleacetic Acid



    • Pyroglutamic Acid
    • 2-Hydroxybutyric Acid

    Ammonia Excess:

    • Orotic Acid

    Aspartame, Salicylates, or GI bacteria:

    • 2-Hydroxyhippuric Acid


    Krebs Cycle Metabolites:

    • Succinic Acid
    • Fumaric Acid
    • Malic Acid
    • 2-Oxoglutaric Acid
    • Aconitic Acid
    • Citric Acid

    Amino Acid Metabolites:

    • 3-Methylglutaric Acid
    • 3-Methylglutaconic
    • 3-Hydroxyglutaric acid


    • 2-Hydroxyisovaleric Acid
    • 3-Methyl-2-oxovaleric Acid
    • 2-Hydroxyisocaproic Acid
    • 2-Oxoisocaproic Acid
    • 2-Oxo-4-methiolbutyric Acid
    • Mandelic Acid
    • Phenyllactic Acid
    • Phenylpyruvic Acid
    • Homogentisic Acid
    • 4-Hydroxyphenyllactic Acid
    • N-Acetylaspartic Acid
    • Malonic Acid

    Tryptophan Metabolites:

    • Glyceric Acid
    • Glycolic Acid
    • Oxalic Acid


    • Lactic Acid
    • Pyruvic Acid


    • Uracil
    • Thymine


    • Phosphoric Acid


    • 3-Hydroxybutyric Acid
    • Acetoacetic Acid
    • 4-Hydroxybutyric Acid
    • Adipic Acid
    • Suberic Acid
    • Sebacic Acid
    • Ethylmalonic Acid
    • Methylsuccinic Acid


    • N-Acetylcysteine Acid
    • Methylcitric Acid
    • Methymalonic Acid (Vit B12)
    • Pyridoxic Acid (Vit B6)
    • Pantothenic Acid (Vit B5)
    • Glutaric Acid (Vit B2)
    • Absorbic Acid (Vit C)
  • FAQs

    What type of sample is required for the Vibrant Organic Acids Test?

    The Vibrant Organic Acids panel is a urine-based assay and performed on mass spectrometry instrumentation, the gold standard in organic acid analysis.

    Should I be fasting for the Organic Acids Test?

    Yes, you should be fasting before providing your sample for the Organic Acids test.

    Should I discontinue any medications or supplements before giving my sample for the Organic Acids test?

    We do not advise discontinuing any necessary medications or supplements and recommend you consult with your prescribing physician or healthcare provider before making any changes to your medication or supplement intake.

    Should I change my diet prior to giving a sample for the Organic Acids test?

    Yes. Some foods can affect the results of an organic acids test result. We recommend avoiding apples, grapes, raisins, pears, cranberries, dried cranberries and any juices from these fruits for 48 hours prior to taking your urine sample.  You should also avoid the following supplements which may affect test results if taken within 48 hrs prior to giving your urine sample: ribose, arabinogalactan, echinacea, and reishi mushrooms.

  • Shipping & Handling

    Vibrant Wellness Lab Tests are Shipped for free within 3-5 business days and include free return shipping instructions.

  • HIPPA Compliance Agreement

    All of your personal information, including the results of your report are processed through Verified HIPPA complient software provided by Vibrant America. 


    As a service provider, IMBTherapies does not maintian owndership of any personal medical records provided to our clients on any company computers or devices.


    You will always have the ability to sign in to a client portal and view your reports, or request a copy of your report be sent to you by contacting be sent to you in the case that you loose any of your documents.   

  • Regulatory Statement

    Vibrant testing does not demonstrate absolute positive and negative predictive values for any disease state or condition. Its clinical utility has not been fully established. Vibrant validates the accuracy and precision of the testing but not of its clinical or diagnostic value. So these tests are for wellness and informational purpose only. Vibrant is actively doing clinical research on these samples, de-identified from patients under an IRB and will make research publications towards the same as and when the clinical utility is well established. These tests have been laboratory developed and their performance characteristics determined by Vibrant America LLC, a CLIA-certified laboratory performing the test CLIA#:05D2078809. The test has not been cleared or approved by the U.S. Food and Drug Administration (FDA). Although FDA does not currently clear or approve laboratory-developed tests in the U.S., certification of the laboratory is required under CLIA to ensure the quality and validity of the tests. The general wellness test intended uses relate to sustaining or offering general improvement to functions associated with a general state of health while making reference to diseases or conditions. Content provided for informational purposes only and should not be construed as medical advice. Content provided to help you make a healthy lifestyle, dietary, and treatment choices in consultation with your healthcare provider. It is intended to be used as a tool to encourage a general state of health and well-being. Please consult with your healthcare practitioner for diagnosis and treatment considerations. The Vibrant Wellness platform provides tools for you to track and analyze your general wellness profile.

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